BIFCA Manual

The Brief International Functional Capacity Assessment (BIFCA) is a performance-based measure of functional capacity that assesses an individual’s ability to perform key tasks of daily living. It is designed to be used as a co-primary outcome measure in clinical trials of cognition-enhancing drugs for adults with schizophrenia and related disorders.

The National Institute of Mental Health (NIMH) Initiative, Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS), was designed to stimulate the development of psychopharmacological agents to improve cognition in schizophrenia and other related disorders. The BIFCA was one deliverable from this Initiative. The development process included:


  • Sponsorship by a government-industry-academic collaboration (MATRICS-CT)
  • Consensus process and collection of empirical data
  • Demonstrated relationship to cognitive deficits and functional outcomes
  • Multiple studies investigating psychometric properties and cross-cultural adaptability of co-primary measures.
  • Subtests selected for their interpretability across cultures
  • Convenient administration, easy to include with other outcome measures

The BIFCA modules assess functional capacity in three areas of basic living skills:

  • Comprehension and planning
  • Household management
  • Work and productivity

Through standardized role-play activities, individuals demonstrate their:

  • Capacity to plan
  • Capacity to identify problems and generate solutions
  • Ability to persist in an activity


The commercial version of the BIFCA is currently offered in the following languages:

– Simplified Chinese
– English
– German
– Hindi
– Japanese
– Spanish – Central and South America
– Spanish – Spain
– Russian