MCCB Neuropsychological Assessment
Purpose of MCCB

The MATRICS Consensus Cognitive Battery (MCCB) is intended to provide a relatively brief evaluation of key cognitive domains relevant to schizophrenia and related disorders, and was designed to address the following purposes:

  • As an outcome measure for clinical trials of cognition-enhancing drugs for schizophrenia
  • As an outcome measure for studies of cognitive remediation
  • As a measure of cognitive change in repeated testing applications
  • As a cognitive reference point for non-intervention studies of schizophrenia and related disorders

The National Institute of Mental Health (NIMH) initiative, Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS), was designed to stimulate the development of psychopharmacological agents to improve cognition in schizophrenia. The MCCB was one deliverable from this Initiative. The selection of tests included in the MCCB involved a broad-based interdisciplinary consensus process that is described in more detail in the following articles:

List of Tests

The MCCB includes ten tests that measure seven cognitive domains:

1. Speed of processing
• BACS: Symbol Coding
• Category Fluency: Animal Naming
• Trail Making Test: Part A

2. Attention/vigilance
• CPT-IP (Trial Testing Only)

3. Working memory
• WMS®-III: Spatial Span
• Letter-Number Span

4. Verbal learning

5. Visual learning

6. Reasoning and problem solving
• NAB®: Mazes

7. Social cognition
• MSCEIT: Managing Emotions

Click to view complete list of tests.

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